{"id":2678,"date":"2026-07-02T21:24:40","date_gmt":"2026-07-02T12:24:40","guid":{"rendered":"https:\/\/saito-cl-liver-regeneration.com\/blog\/?p=2678"},"modified":"2026-07-02T21:27:25","modified_gmt":"2026-07-02T12:27:25","slug":"post-2678","status":"publish","type":"post","link":"https:\/\/saito-cl-liver-regeneration.com\/blog\/post-2678\/","title":{"rendered":"[A Hepatologist Explains] Your Body Itches at Night… Could It Be a Sign from Your Internal Organs? How to Tell It Apart from Dry Skin and Eczema"},"content":{"rendered":"
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I am Masaya Saito, Director of Saito Clinic of Internal Medicine in Nishi-ku, Kobe.<\/p>\n\n\n\n

“I get so itchy when I get into bed at night that I can’t sleep.”<\/em><\/p>\n\n\n\n

“My whole body itches even though there’s nothing on my skin.”<\/em><\/p>\n\n\n\n

Are you troubled by such unexplained itching?<\/p>\n\n\n\n

When people think of itching, many imagine red, swollen skin or bumpy rashes caused by bug bites or contact dermatitis. Most of these types of itching fall under the category of skin troubles.<\/p>\n\n\n\n

However, there is also “itching caused by something other than the skin” that presents no visible abnormalities.<\/p>\n\n\n\n

In this article, a hepatologist will explain in detail how to distinguish this “dangerous itching originating from internal organs”\u2014which differs from dry skin or eczema\u2014and the terrifying diseases hidden behind it.<\/p>\n\n\n\n

\u25a01. What is “Pruritus” Without a Rash?<\/strong><\/h2>\n\n\n
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It has long been said that “the skin is the mirror of the internal organs.” This means that some skin diseases are deeply related to internal organ lesions. Skin lesions associated with internal organ diseases are called “dermadromes.”<\/p>\n\n\n\n

If you experience intense itching despite the absence of visible rashes or lesions (like eczema or hives) on your skin, it might be “pruritus” (skin itching without a primary rash).<\/p>\n\n\n\n

Pruritus, in particular, tends to become more severe at night before going to sleep. This is thought to be influenced by factors such as a rise in body temperature, parasympathetic nervous system dominance, and the mind being conscious and awake.<\/p>\n\n\n\n

If you leave it alone, assuming it is “just dry skin,” a serious problem may actually be occurring inside your body.<\/p>\n\n\n\n

\u25a02. [Caution Required] 5 Characteristics of Itching Caused by Liver Disease<\/strong><\/h2>\n\n\n\n
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If you have itching despite no noticeable abnormalities on your skin, there is a possibility that a problem with your internal organ functions, such as liver disease, is hidden.<\/p>\n\n\n\n

Itching caused by liver disease is thought to occur when the flow of bile produced in the liver worsens, causing bile components to accumulate excessively in the skin. There are also research findings suggesting that substances in the body called “opioids” are involved.<\/p>\n\n\n\n

Itching due to liver disease is said to have the following characteristics. Please compare them with your own symptoms:<\/p>\n\n\n\n