{"id":2866,"date":"2026-07-14T07:35:37","date_gmt":"2026-07-13T22:35:37","guid":{"rendered":"https:\/\/saito-cl-liver-regeneration.com\/blog\/?p=2866"},"modified":"2026-07-14T07:36:31","modified_gmt":"2026-07-13T22:36:31","slug":"post-2866","status":"publish","type":"post","link":"https:\/\/saito-cl-liver-regeneration.com\/blog\/post-2866\/","title":{"rendered":"\u3010\u809d\u81d3\u75c5\u5c02\u9580\u533b\u304c\u89e3\u8aac\u3011\u809d\u786c\u5909\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32026\u5e74\u6539\u8a02\u7248\u306e\u6ce8\u76ee\u30dd\u30a4\u30f3\u30c8\u2014\u8840\u5c0f\u677f\u6e1b\u5c11\u30fb\u8179\u6c34\u30fb\u809d\u814e\u75c7\u5019\u7fa4\u306e\u6700\u65b0\u6cbb\u7642"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

\u79c1\u306f\u3053\u308c\u307e\u3067\u3001\u809d\u786c\u5909\u306e\u5408\u4f75\u75c7\u7ba1\u7406\u306b\u95a2\u9023\u3059\u308b\u8907\u6570\u306e\u7814\u7a76\u3092\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u809d\u7dda\u7dad\u5316\u306e\u8a55\u4fa1\u306b\u3064\u3044\u3066\u306f\u3001\u8ad6\u6587\u300cHepatol Mon 2015; 15(2): e22978 \u2014\u2014NX-DCP\u30e2\u30c7\u30eb\u306b\u3088\u308b\u975e\u4fb5\u8972\u7684\u809d\u7dda\u7dad\u5316\u8a3a\u65ad\u300d\u306b\u304a\u3044\u3066\u3001\u8840\u6db2\u691c\u67fb\u304b\u3089\u5f97\u3089\u308c\u308bNX-DCP\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u975e\u4fb5\u8972\u7684\u306a\u809d\u7dda\u7dad\u5316\u8a3a\u65ad\u6cd5\u306e\u6709\u7528\u6027\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002\u809d\u751f\u691c\u3092\u884c\u308f\u305a\u306b\u809d\u81d3\u306e\u7dda\u7dad\u5316\u30b9\u30c6\u30fc\u30b8\u3092\u63a8\u5b9a\u3067\u304d\u308b\u3053\u306e\u30e2\u30c7\u30eb\u306f\u3001\u60a3\u8005\u69d8\u306e\u8eab\u4f53\u7684\u8ca0\u62c5\u3092\u6e1b\u3089\u3057\u306a\u304c\u3089\u65e9\u671f\u306b\u6cbb\u7642\u4ecb\u5165\u306e\u5224\u65ad\u3092\u884c\u3046\u306e\u306b\u6709\u7528\u3067\u3059\u3002<\/p>\n\n\n\n

\u203b\u53c2\u8003\u8ad6\u6587\uff1a<\/h3>\n\n\n\n

https:\/\/brieflands.com\/journals\/hepatmon\/articles\/15446<\/a><\/p>\n\n\n\n

\u307e\u305f\u3001\u809d\u6027\u8133\u75c7\u306e\u6804\u990a\u7ba1\u7406\u306b\u3064\u3044\u3066\u306f\u3001\u8ad6\u6587\u300cHepatol Res 2016; 46(2): 215-224\u300d\u306b\u304a\u3044\u3066\u3001\u6f5c\u5728\u6027\u809d\u6027\u8133\u75c7\u306b\u5bfe\u3059\u308b\u300cL-\u30ab\u30eb\u30cb\u30c1\u30f3\u300d\u306e\u88dc\u5145\u52b9\u679c\u3068\u3001\u305d\u306e\u52b9\u679c\u3092\u4e88\u6e2c\u3059\u308b\u56e0\u5b50\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u6cbb\u7642\u524d\u306e\u8840\u6db2\u4e2d\u306b\u3042\u308b\u300c\u30bf\u30a6\u30ea\u30f3\u300d\u306e\u6fc3\u5ea6\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001L-\u30ab\u30eb\u30cb\u30c1\u30f3\u306b\u3088\u308b\u6cbb\u7642\u52b9\u679c\u304c\u5f97\u3089\u308c\u3084\u3059\u3044\u60a3\u8005\u69d8\u3092\u4e8b\u524d\u306b\u9ad8\u3044\u7cbe\u5ea6\u3067\u4e88\u6e2c\u3067\u304d\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u60a3\u8005\u69d8\u304a\u4e00\u4eba\u304a\u3072\u3068\u308a\u306b\u9069\u3057\u305f\u7121\u99c4\u306e\u306a\u3044\u6804\u990a\u7642\u6cd5\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u203b\u53c2\u8003\u8ad6\u6587\uff1a<\/h3>\n\n\n\n

ht<\/a>tps:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hepr.12565<\/a><\/p>\n\n\n\n

\u3053\u308c\u3089\u306e\u7814\u7a76\u3092\u901a\u3058\u3066\u57f9\u3063\u305f\u77e5\u898b\u3092\u6d3b\u304b\u3057\u3001\u5f53\u9662\u3067\u306f\u809d\u786c\u5909\u306e\u60a3\u8005\u69d8\u306e\u8840\u6db2\u691c\u67fb\u30fb\u753b\u50cf\u691c\u67fb\u306e\u7d50\u679c\u3092\u8a73\u7d30\u306b\u89e3\u6790\u3057\u3001\u3088\u308a\u7cbe\u5ea6\u306e\u9ad8\u3044\u75c5\u614b\u8a55\u4fa1\u3068\u6cbb\u7642\u65b9\u91dd\u306e\u6c7a\u5b9a\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u25a05. \u809d\u786c\u5909\u306e\u6839\u6cbb\u3092\u76ee\u6307\u3059\uff1a\u518d\u751f\u533b\u7642\u3068\u3044\u3046\u6700\u65b0\u306e\u6cbb\u7642\u9078\u629e\u80a2<\/h2>\n\n\n
\n
\"\"<\/figure>\n<\/div>\n\n\n

2026\u5e744\u6708\u3001\u9577\u5d0e\u5927\u5b66\u75c5\u9662\u306a\u3069\u304c\u4e16\u754c\u3067\u521d\u3081\u3066CLiP\u7d30\u80de\uff08Chemically-induced Liver Progenitor cells\uff1a\u5316\u5b66\u8a98\u5c0e\u809d\u524d\u99c6\u7d30\u80de\uff09\u3092\u7528\u3044\u305f\u809d\u786c\u5909\u518d\u751f\u533b\u7642\u306e\u81e8\u5e8a\u7814\u7a76\u3092\u958b\u59cb\u3057\u305f\u3053\u3068\u304c\u5927\u304d\u306a\u8a71\u984c\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u809d\u786c\u5909\u306e\u60a3\u8005\u69d8\u306e\u809d\u81d3\u306b\u91dd\u3092\u523a\u3057\u3066\u4e00\u90e8\u306e\u809d\u7d44\u7e54\u3092\u63a1\u53d6\u3057\u3001\u5f97\u3089\u308c\u305f\u809d\u7d30\u80de\u306b3\u7a2e\u985e\u306e\u85ac\u5264\uff08\u4f4e\u5206\u5b50\u5316\u5408\u7269\uff09\u3092\u52a0\u3048\u3066\u7d0490\u65e5\u9593\u57f9\u990a\u3059\u308b\u3053\u3068\u3067\u3001\u809d\u7d30\u80de\u306b\u5206\u5316\u3067\u304d\u308b\u80fd\u529b\u3092\u6301\u3064CLiP\u7d30\u80de\u3092\u4f5c\u88fd\u3057\u3001\u518d\u3073\u60a3\u8005\u69d8\u306e\u809d\u81d3\u306b\u623b\u3059\u3068\u3044\u3046\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002<\/p>\n\n\n\n

CLiP\u7d30\u80de\u306e\u7279\u9577\u306f\u3001\u60a3\u8005\u69d8\u81ea\u8eab\u306e\u7d30\u80de\u3092\u4f7f\u3046\u305f\u3081\u62d2\u7d76\u53cd\u5fdc\u304c\u8d77\u304d\u306b\u304f\u304f\u3001iPS\u7d30\u80de\u3088\u308a\u3082\u5927\u91cf\u57f9\u990a\u304c\u5bb9\u6613\u3067\u3042\u308b\u70b9\u3067\u3059\u30022028\u5e743\u6708\u307e\u3067\u306b3\u540d\u306b\u5b9f\u65bd\u3057\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u30015\u301c10\u5e74\u5f8c\u306e\u5b9f\u7528\u5316\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u305f\u3060\u3001\u809d\u81d3\u306b\u76f4\u63a5\u3001\u91dd\u3092\u523a\u3057\u3066\u809d\u7d44\u7e54\u3092\u56de\u53ce\u3059\u308b\u3068\u3044\u3046\u624b\u6280\u304c\u3001\u4fb5\u8972\u5ea6\u304c\u9ad8\u304f\u51fa\u8840\u30ea\u30b9\u30af\u304c\u3042\u308b\u3053\u3068\u304b\u3089\u3001Child-Pugh C\u306e\u975e\u4ee3\u511f\u6027\u809d\u786c\u5909\u60a3\u8005\u69d8\u3067\u306f\u6cbb\u7642\u9069\u5fdc\u5916\u3067\u3042\u308b\u3053\u3068\u306f\u5ff5\u982d\u306b\u7f6e\u3044\u3066\u304a\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u3053\u306e\u3088\u3046\u306a\u6700\u5148\u7aef\u306e\u518d\u751f\u533b\u7642\u306e\u30cb\u30e5\u30fc\u30b9\u304c\u5e83\u307e\u308b\u306b\u3064\u308c\u3066\u3001\u5f53\u9662\u3067\u3082\u3001\u5f93\u6765\u306e\u6a19\u6e96\u6cbb\u7642\uff08\u85ac\u7269\u7642\u6cd5\u30fb\u98df\u4e8b\u7642\u6cd5\u30fb\u5408\u4f75\u75c7\u7ba1\u7406\uff09\u306b\u52a0\u3048\u3066\u3001\u518d\u751f\u533b\u7642\u306e\u9069\u5fdc\u306b\u3064\u3044\u3066\u306e\u3054\u76f8\u8ac7\u304c\u5897\u3048\u3066\u304d\u3066\u3044\u307e\u3059\u3002\u5f53\u9662\u3067\u306f2024\u5e744\u6708\u304b\u3089\u3001\u60a3\u8005\u69d8\u3054\u81ea\u8eab\u306e\u304a\u5c3b\u306e\u8102\u80aa\u7d44\u7e54\u304b\u3089\u62bd\u51fa\u3057\u305f\u5e79\u7d30\u80de\u3092\u7528\u3044\u305f\u300c\u81ea\u5df1\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u70b9\u6ef4\u7642\u6cd5\u300d\u3092\u63d0\u4f9b\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u81e8\u5e8a\u7814\u7a76\u6bb5\u968e\u306eCLiP\u7d30\u80de\u306b\u3088\u308b\u6cbb\u7642\u3068\u306f\u7570\u306a\u308a\u3001\u5f53\u9662\u3067\u63d0\u4f9b\u3057\u3066\u3044\u308b\u518d\u751f\u533b\u7642\u306f\u3001Child-Pugh C\u306e\u975e\u4ee3\u511f\u6027\u809d\u786c\u5909\u60a3\u8005\u69d8\u306b\u3082\u9069\u5fdc\u304c\u3042\u308a\u3001\u4eca\u3059\u3050\u53d7\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u518d\u751f\u533b\u7642\u3068\u3057\u3066\u78ba\u304b\u306a\u5b9f\u7e3e\u3092\u7a4d\u3093\u3067\u304a\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u65e5\u672c\u56fd\u5185\u3060\u3051\u306b\u7559\u307e\u3089\u305a\u3001\u6d77\u5916\u306e\u809d\u786c\u5909\u60a3\u8005\u69d8\u304c\u308f\u3056\u308f\u3056\u6765\u65e5\u3057\u3066\u53d7\u3051\u306b\u6765\u3089\u308c\u308b\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u73fe\u5728\u6ce8\u76ee\u3092\u6d74\u3073\u3066\u3044\u307e\u3059\u3002\u809d\u786c\u5909\u3068\u8a3a\u65ad\u3055\u308c\u3066\u3044\u308b\u65b9\u3067\u300c\u518d\u751f\u533b\u7642\u306b\u3064\u3044\u3066\u77e5\u308a\u305f\u3044\u300d\u300c\u4eca\u306e\u6cbb\u7642\u3067\u3088\u3044\u306e\u304b\u78ba\u8a8d\u3057\u305f\u3044\u300d\u3068\u3044\u3046\u65b9\u306f\u3001\u305c\u3072\u5f53\u9662\u307e\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n

\u25a06. \u307e\u3068\u3081\uff1a\u809d\u786c\u5909\u306e\u7ba1\u7406\u306f\u809d\u81d3\u75c5\u5c02\u9580\u533b\u3068\u306e\u7d99\u7d9a\u7684\u306a\u9023\u643a\u304c\u9375<\/h2>\n\n\n
\n
\"\"<\/figure>\n<\/div>\n\n\n

2026\u5e74\u306e\u809d\u786c\u5909\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u6539\u8a02\u3067\u306f\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u6cbb\u7642\u85ac\uff08\u30eb\u30b9\u30c8\u30ed\u30f3\u30dc\u30d1\u30b0\u30fb\u30a2\u30d0\u30c8\u30ed\u30f3\u30dc\u30d1\u30b0\uff09\u306e\u65b0\u305f\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u3001\u809d\u814e\u75c7\u5019\u7fa4\uff08HRS-AKI\uff09\u3078\u306e\u30c6\u30eb\u30ea\u30d7\u30ec\u30b7\u30f3\u306e\u4f7f\u7528\u3001\u8179\u6c34\u7ba1\u7406\u306e\u6700\u65b0\u77e5\u898b\u306a\u3069\u3001\u5b9f\u81e8\u5e8a\u306b\u76f4\u7d50\u3059\u308b\u5185\u5bb9\u304c\u66f4\u65b0\u3055\u308c\u308b\u898b\u8fbc\u307f\u3067\u3059\u3002<\/p>\n\n\n\n

\u91cd\u8981\u306a\u306e\u306f\u3001\u3053\u308c\u3089\u306e\u6cbb\u7642\u306e\u6069\u6075\u3092\u6700\u5927\u9650\u306b\u53d7\u3051\u308b\u305f\u3081\u306b\u306f\u3001\u65e9\u671f\u304b\u3089\u306e\u809d\u81d3\u75c5\u5c02\u9580\u533b\u306b\u3088\u308b\u7ba1\u7406\u3068\u3001\u5b9a\u671f\u7684\u306a\u691c\u67fb\u306b\u3088\u308b\u5408\u4f75\u75c7\u306e\u65e9\u671f\u767a\u898b\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3068\u3044\u3046\u70b9\u3067\u3059\u3002\u809d\u786c\u5909\u306f\u5b8c\u5168\u306b\u306f\u5143\u306b\u623b\u308a\u307e\u305b\u3093\u304c\u3001\u9069\u5207\u306a\u7ba1\u7406\u306b\u3088\u3063\u3066\u4ee3\u511f\u671f\u3092\u9577\u304f\u7dad\u6301\u3057\u3001\u751f\u6d3b\u306e\u8cea\uff08QOL\uff09\u3092\u4fdd\u3064\u3053\u3068\u304c\u5341\u5206\u306b\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n

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